Introducing a new web series from Peapod Bio! In this series, CEO Zachary Gurard-Levin, PhD talks about the nuances of developing robust assays for small molecule drug discovery. He speaks with other assay experts about critical factors to consider that often extend beyond the assay well and protocol. Stay tuned every two weeks for new episodes!
Episode 3 – Hey Joe Franklin, Get Your Head Out of Your Assay! In this episode, we talk with fellow Boston-native Joe Franklin, President and Co-Founder of Method Discovery Services, who shares insights from over two decades of hands-on experience building, designing, executing, and analyzing DNA-encoded library (DEL) screens for small molecule drug discovery. He discusses how key aspects to consider during assay design and data interpretation, and what separates high-quality screens from noisy ones. The conversation also highlights how artificial intelligence and machine learning (AI/ML) tools are integrated in data analysis workflows to highlight promising hits for further development.
Pilot: Hey Michael Scholle, Get your head out of your assay!. In this episode, we walk with Michael Scholle, CEO of Tango Biosciences, to explore the importance of cadence when designing assays with multiple reagent dispenses to ensure consistent activity across every plate.
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Assay
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High-Throughput
Screening
Affinity Selection
Mass Spectrometry
Small Molecule Libraries
