Acetyltransferase assays using MALDI MS and polymeric enrichment arrays (PEAs)

Acetyltransferase enzymes are key players implicated in gene expression regulation, DNA replication and repair, where perturbation is associated with various diseases including cancer. Traditional assays rely on labels that lack selectivity or focus on cofactor metabolism, generating indirect measurements that can lead researchers down the wrong path. Learn how Peapod Bio’s innovative mass spectrometry assay offers the ability to directly measure substrate acetylation, including multiple acetylation events, providing clear, interpretable data faster to drive projects forward.