Scientific Resources
Search our resources — articles, case studies, presentations, and more — for answers to your biggest assay inquiries and drug discovery questions.
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Three Pillars of Early Drug Discovery Success: Part 1: Introduction to druggability, ligandability, and assayability
This white paper introduces a framework for evaluating early drug discovery programs through three interconnected pillars: druggability, ligandability, and assayability. It defines druggability as the likelihood that a target can be modulated by a therapeutic molecule, ligandability as the ability to identify compounds that bind to that target, and assayability as the ability to reliably measure the target’s…
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Frequently Asked Questions
Learn more about Peapod Bio’s rapid, decision-driving solutions for small molecule and peptide drug discovery.
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200,000 reasons to be confident in your HTS data.
Download our technote to take a deeper dive into Peapod Bio’s curated diversity compound library that features valuable properties to initiate any small molecule drug discovery program. Available as single compounds for biochemical high-throughput screening using our label-free MALDI-MS and polymeric enrichment array technology or optical methodologies and in pools of twelve for affinity selection…
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Assay development and HTS of PAPD5 inhibitors using an innovative mass spectrometry platform
Abstract: The Poly Adenosine Polymerase Associated domain 5 and 7 proteins regulate RNA stability by adding adenosine nucleotides to the 3’ end of various RNAs, including telomeric RNA, oncogenic microRNAs (miRNA) and viral RNA such as Hepatitis B Virus (HBV). Inhibitors of PAPD5 and PAPD7 offer promising therapeutic avenues to combat certain cancers, telomere-biology disorders,…
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Why combining MALDI-MS and PEAs became the perfect assay for “me”
Download this tech note to see how combining MALDI MS and PEAs is ideally suited for measuring methyltransferase activities and characterizing MTase inhibitors.
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Measuring kinases and phosphatases using high-throughput MALDI and PEAs
Download our tech note to learn how surface chemistry and MALDI MS is driving the discovery and characterization of kinase and phosphatase inhibitors.
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