Scientific Resources
Search our resources — articles, case studies, presentations, and more — for answers to your biggest assay inquiries and drug discovery questions.
FAQ
Frequently Asked Questions
Learn more about Peapod Bio’s rapid, decision-driving solutions for small molecule and peptide drug discovery.
All Peapod Bio Resources
Sort by Type
Search Resources
-
Three Pillars of Early Drug Discovery Success Part 3: Assayability: A Practical Framework for Target Validation and Hit Identification
The first two papers in this three-part series established the foundational framework of early drug discovery: druggability, ligandability, and assayability, and explored why assayability is often the most consequential and underappreciated determinant of program success. This third (and final) white paper translates that strategic framework into practice. Here we address the central operational question: How…
-
Three Pillars of Early Drug Discovery Success Part 2: Assayability – The Hidden Determinant of Drug Discovery Success
Drug discovery is an exercise in measurement. Every decision made during target validation, hit identification, and lead optimization depends on data generated by assays. Yet assay quality (beyond Z-factors and assay windows) remains one of the most underappreciated determinants of discovery success. Conversely, assay failure is one of the most underappreciated sources of program attrition.This…
-
Three Pillars of Early Drug Discovery Success: Part 1: Introduction to druggability, ligandability, and assayability
This white paper introduces a framework for evaluating early drug discovery programs through three interconnected pillars: druggability, ligandability, and assayability. It defines druggability as the likelihood that a target can be modulated by a therapeutic molecule, ligandability as the ability to identify compounds that bind to that target, and assayability as the ability to reliably measure the target’s…
-
Frequently Asked Questions
Learn more about Peapod Bio’s rapid, decision-driving solutions for small molecule and peptide drug discovery.
-
200,000 reasons to be confident in your HTS data.
Download our technote to take a deeper dive into Peapod Bio’s curated diversity compound library that features valuable properties to initiate any small molecule drug discovery program. Available as single compounds for biochemical high-throughput screening using our label-free MALDI-MS and polymeric enrichment array technology or optical methodologies and in pools of twelve for affinity selection…
-
Assay development and HTS of PAPD5 inhibitors using an innovative mass spectrometry platform
Abstract: The Poly Adenosine Polymerase Associated domain 5 and 7 proteins regulate RNA stability by adding adenosine nucleotides to the 3’ end of various RNAs, including telomeric RNA, oncogenic microRNAs (miRNA) and viral RNA such as Hepatitis B Virus (HBV). Inhibitors of PAPD5 and PAPD7 offer promising therapeutic avenues to combat certain cancers, telomere-biology disorders,…
Explore Peapod Bio Solutions
Assay
Development
High-Throughput
Screening
Affinity Selection
Mass Spectrometry
Small Molecule Libraries
Ready to generate results?