High-Throughput Screening
High-quality data at high-throughput speeds
Choosing Peapod Bio’s hit identification solutions for your high-throughput screening project will accelerate your discovery program with our tailored, flexible approach.
Our label-free technology and efficient optical assay solutions enable our team to screen a million compounds per week, delivering decision-making data in your hands in as little as 24 hours. We offer solutions including assay setup, preparation, and execution for the following screening phases:
| PHASE | DESCRIPTION |
|---|---|
| Pilot HTS | Assess hit rates and ligandability to determine the optimal conditions for your screen. |
| Full HTS Campaigns | Benefit from label-free or optical assays to screen our compounds and/or your own library to identify small molecule modulators of your enzyme activity or binders to your protein or oligonucleotide target. |
| Hit Confirmation | Re-evaluate hits identified in your HTS for added confidence. |
| IC50s and Mechanism of Action | Characterize your hits in concentration response curves to determine potency, selectivity, and mechanism of action using orthogonal methodologies. |
| Hit Expansion and Lead Optimization | Evaluate structure activity relationship (SAR) and identify critical moieties for optimal target engagement. |
Assay
Development
High-Throughput
Screening
Affinity Selection
Mass Spectrometry
Small Molecule Libraries
Tech Note
HTS for sortase A inhibitors using MALDI MS and polymeric enrichment arrays (PEAs)
Download our tech note to learn how Peapod Bio’s innovative technology is ideal to measure distinct activities simultaneously.
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